Chemistry LibreTexts - General Mechanism for Nucleophilic Addition-Elimination Reactions
Virtual Textbook of Organic Chemistry - Substitution of the Hydroxyl Group of Carboxylic Acids
Purdue University - Addition/Elimination Reactions of Carboxylic Acid Derivatives
Great place to review one of the most important general reaction mechanisms for the MCAT.
Virtual Textbook of Organic Chemistry - Acyl Group SubstitutionVirtual Textbook of Organic Chemistry - Substitution of the Hydroxyl Group of Carboxylic Acids
Purdue University - Addition/Elimination Reactions of Carboxylic Acid Derivatives
Solid presentation of the fundamentals of acyl transfer (addition/elimination) reactions.
Master Organic Chemistry - Simplifying the reactions of carboxylic acid derivatives (part 1)Helpful discussion. This is an important theme in biochemistry.
Topic Resources
Interdisciplinary MCAT Course Videos
14 questions
- Acyl Substitution - Saponification
- Acyl Substitution - Aminolysis
- Acyl Substitution - Esterification of Anhydrides
- Chymotrypsin
- Acyl CoA Synthetase
- Triglyceride Synthesis
- Nitrile Hydrolysis
- Reduction of Carboxylic Acids
- HMG-CoA Reductase
- Decarboxylation of a β-Keto Acid
- Decarboxylation of an α-Keto Acid by α-Ketoglutarate Dehydrogenase
- Formation and Use of a Carboxylate Nucleophile
- Glutamine Synthetase
- Lactones & Lactams
- Inhibition of Transpeptidase by Penicillin
figures for classroom presentation