Comparison of non-integrating plasmids (top) and episomes (bottom). Top: Chromosomal DNA and plasmids replicated separately. Bottom: Chromosomal DNA with integrated plasmids replicate as a single chromosome.

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Comparison of non-integrating plasmids (top) and episomes (bottom). Top: Chromosomal DNA and plasmids replicated separately. Bottom: Chromosomal DNA with integrated plasmids replicate as a single chromosome.